(R) -CJ 11974
(R) -CJ 11974 is a non-peptide, enantiomerically pure antagonist of the neurokinin-1 (NK1) receptor. It is utilized in research to investigate mechanisms of pain and chemotherapy-induced nausea, with studies demonstrating its activity in both in vitro receptor binding assays and in vivo animal models.
Product Specifications
CAS Number
187281-35-2
Product Name Alternative
CJ11974, CJ-11974, CJ 11974, (R) CJ11974, Neurokininreceptor, Neurokinin receptor, NK1
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
96.08% (May vary between batches)
Solubility
DMSO:55 mg/mL (120.97 mM)
Smiles
[C@@H] ([C@@H]1[C@H] (NCC2=C (OC) C=CC (C (C) C) =C2) C3CCN1CC3) (C4=CC=CC=C4) C5=CC=CC=C5
Molecular Formula
C31H38N2O
Molecular Weight
454.65
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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