P3FI-63
P3FI-63 is a KDM3B inhibitor with a IC50 value of 7 μM. P3FI-63 has antitumor activity[1].
Product Specifications
CAS Number
[931596-95-1]
UNSPSC
12352005
Target
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/p3fi-63.html
Concentration
10mM
Purity
98.35
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NNC(C1=CC(C)=CC(C)=C1)=O)C2=NC=CC=C2
Molecular Formula
C15H15N3O2
Molecular Weight
269.30
References & Citations
[1]Kim YY, et al. KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma. Nat Commun. 2024 Feb 24;15 (1) :1703.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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