BMS-309403 sodium
BMS-309403 sodium is a potent, orally active, and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor, with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 sodium interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 sodium improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells.
Product Specifications
CAS Number
2802523-05-1
Purity
>98%
Smiles
C (C1N (C2C=CC=CC=2C2C=CC=C (OCC (=O) O) C=2) N=C (C2C=CC=CC=2) C=1C1C=CC=CC=1) C.[NaH]
Molecular Formula
C31H27N2NAO3
Molecular Weight
498.5474588871
Notes
For research use only.
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