Epoxiconazole

Epoxiconazole, a fungicide, is a demethylation inhibitor of the Ergosterol biosynthesis pathway. Epoxiconazole exhibits strong inhibitory effects on both carbendazim-resistant and phenamacril-resistant isolates, and can be used for controlling many crop diseases[1].

Product Specifications

CAS Number

[133855-98-8]

UNSPSC

12352005

Hazard Statement

H351, H411

Target

Apoptosis; Fungal

Type

Reference compound

Related Pathways

Anti-infection; Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/epoxiconazole.html

Purity

98.95

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

FC1=CC=C(C=C1)[C@]2(O[C@@H]2C3=CC=CC=C3Cl)CN4N=CN=C4

Molecular Formula

C17H13ClFN3O

Molecular Weight

329.76

Precautions

H351, H411

References & Citations

[1]Yabing Duan, et al. Impact of Epoxiconazole on Fusarium Head Blight Control, Grain Yield and Deoxynivalenol Accumulation in Wheat. Pestic Biochem Physiol. 2018 Nov;152:138-147.|[2]Hamdi H, et al., Neuroprotective effects of Myricetin on Epoxiconazole-induced toxicity in F98 cells. Free Radic Biol Med. 2021 Feb 20;164:154-163.|[3]Sun W, et al., Combined ingestion of polystyrene microplastics and epoxiconazole increases health risk to mice: Based on their synergistic bioaccumulation in vivo. Environ Int. 2022 Aug;166:107391.