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Capsid assembly inhibitor

Capsid assembly inhibitor is a 12-mer peptide that binds the capsid (CA) domain of Gag and inhibits assembly of immature- and mature-like HIV-1 capsid particles in vitro[1].

Product Specifications

CAS Number

[865292-94-0]

UNSPSC

12352209

Target

HIV

Type

Peptides

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CC3=CC=C(C=C3)O)C(NCC(N4[C@@H](CCC4)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@@H](C)CC)N

Molecular Formula

C69H96N12O22

Molecular Weight

1445.57

References & Citations

[1]Sticht J, et al. A peptide inhibitor of HIV-1 assembly in vitro. Nat Struct Mol Biol. 2005 Aug;12 (8) :671-7.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

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