IC-8
IC8 is an ionizable cationic lipid. It has been used in combination with other lipids for the formation of lipid nanoparticles (LNPs) . Immunization with severe acute respiratory coronavirus 2 (SARS-CoV-2) spike glycoprotein mRNA in IC8- and manganese-containing LNPs induces IgG responses to SARS-CoV-2 Delta and Omicron variants in mice.1 Administration of mRNA encoding B7-H3 X CD3 bispecific T cell engaging (BiTE) antibodies in IC8-containing LNPs reduces tumor growth in MV4-11 and A375 mouse xenograft models.
Product Specifications
CAS Number
2349307-32-8
Purity
>95%
Smiles
OC (CCCCCCCCCCCC) CN (CC (CCCCCCCCCCCC) O) CCCN1CCN (CCCN (CC (CCCCCCCCCCCC) O) CC (CCCCCCCCCCCC) O) CC1
Molecular Formula
C66H136N4O4
Molecular Weight
1049.8
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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