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UHRF1 PHD inhibitor MLD4

UHRF1 PHD inhibitor MLD4 is a specific compound that selectively inhibits the UHRF1-histone interaction (IC50=12.4 uM), targets the PHD finger of UHRF1, specifically disrupting histone H3 arginine 2 interactions with the PHD finger.UHRF1 PHD inhibitor MLD4 inhibited binding between H3K9me3 (FAM) and UHRF1 with IC50 of 24-26 uM, displace UHRF1-histone H3 binding in cells.

Product Specifications

CAS Number

922067-76-3

Field of Research

Epigenetics & Chromatin; Pharmacology & Drug Discovery

Purity

>98%

Molecular Formula

C22H32N4O4

Molecular Weight

416.522

Notes

For research use only.

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