UHRF1 PHD inhibitor MLD4
UHRF1 PHD inhibitor MLD4 is a specific compound that selectively inhibits the UHRF1-histone interaction (IC50=12.4 uM), targets the PHD finger of UHRF1, specifically disrupting histone H3 arginine 2 interactions with the PHD finger.UHRF1 PHD inhibitor MLD4 inhibited binding between H3K9me3 (FAM) and UHRF1 with IC50 of 24-26 uM, displace UHRF1-histone H3 binding in cells.
Product Specifications
CAS Number
922067-76-3
Field of Research
Epigenetics & Chromatin; Pharmacology & Drug Discovery
Purity
>98%
Molecular Formula
C22H32N4O4
Molecular Weight
416.522
Notes
For research use only.
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