Pamidronic acid
Pamidronic acid is a bisphosphonate compound used in research to study osteonecrosis mechanisms. It inhibits osteogenic differentiation in human bone marrow mesenchymal stem cells by suppressing Wnt/β-catenin signaling, a pathway critical for bone formation. This makes it a valuable tool for in vitro models of bone metabolism disorders and drug-induced osteonecrosis.
Product Specifications
CAS Number
40391-99-9
Product Name Alternative
Inhibitor, Pamidronic acid, inhibit, beta-catenin, betacatenin, Beta catenin, bcatenin, Wnt/β-catenin, Wnt, Wnt/betacatenin, Wnt/b-catenin, β-catenin, βcatenin
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Purity
97.72% (May vary between batches)
Solubility
H2O:6 mg/mL (25.52 mM)
Smiles
O.O.O.O.O.[Na+].[Na+].NCCC (O) (P (O) ([O-]) =O) P (O) ([O-]) =O
Molecular Formula
C3H11NO7P2
Molecular Weight
235.07
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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