Fasudil
Fasudil (HA-1077) is a cell-permeable, potent inhibitor targeting ROCK1, PKA, PKC, and MLCK kinases. It is widely used in cardiovascular and neurological research, demonstrating efficacy in both in vitro assays and in vivo models of vasospasm and neurodegeneration.
Product Specifications
CAS Number
103745-39-7
Product Name Alternative
Ca2+ channel antagonist, Ca2+ channels, Calcium Channel, Ca channels, Autophagy, AT 877, AT877, AT-877, a-SMA, collagen, CalciumChannel, lysophoaphatidic acid, LPA, MLCK, orally active, inhibit, JNK, ERK1/2, Fasudil, HA 1077, HA1077, HA-1077, Inhibitor, human HSC, p38, Serine kinase, threoninkinase, threonin kinase, Serinekinase, PKC, PKA, PKG, rat HSCs, TIMP-1, Protein kinase A, protein kinases, Protein kinase C, ROCK, ROCK2, ROK, Rho-kinase, Rho-associated protein kinase, Rho-associated kinase, TWNT-4 cells, vasodilator
Field of Research
Cell Biology, Epigenetics & Chromatin, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.79% (May vary between batches)
Solubility
DMSO:61.875 mg/mL (212.36 mM)
Smiles
O=S (=O) (N1CCCNCC1) c1cccc2cnccc12
Molecular Formula
C14H17N3O2S
Molecular Weight
291.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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