ThioLox
ThioLox is a potent and competitive 15-LOX-1 inhibitor (IC50 = 12 μM) with demonstrated neuroprotective and anti-inflammatory properties. It has shown protective effects against glutamate-induced toxicity in cellular models, supporting its research utility in studying oxidative stress and neuroinflammation pathways.
Product Specifications
CAS Number
1202193-89-2
Product Name Alternative
15 LOX, ThioLox
Field of Research
Metabolism Research
Purity
99.98% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (12.03 mM) ; DMSO:90 mg/mL (328.01 mM)
Smiles
C (NCCCC) (=O) C=1C=C (SC1N) C2=CC=CC=C2
Molecular Formula
C15H18N2OS
Molecular Weight
274.38
Storage Conditions
-20°C
Notes
For research use only.
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