Copper histidine
This research compound, copper histidine, inhibits the Ctr1 transporter to block oxaliplatin uptake in vitro, yet does not affect platinum accumulation or neurotoxicity in DRG tissues in vivo. It is a key agent for studying copper metabolism, Menkes disease, and mechanisms of platinum-based chemotherapeutic resistance and neurotoxicity.
Product Specifications
CAS Number
77280-83-2
Field of Research
Pharmacology & Drug Discovery
Purity
96.81% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:< 1 mg/mL (insoluble or slightly soluble)
Smiles
O=C1[O-][Cu+2]2[N]3 (C (C[C@@]1 ([NH2]2) [H]) =CN=C3) [H]
Molecular Formula
C6H8CuN3O2
Molecular Weight
217.69
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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