HRO761
HRO761 is a potent and selective inhibitor of the Werner syndrome RecQ DNA helicase (WRN), a promising target for synthetic lethality in microsatellite unstable (MSI) cancers. It is a valuable research tool for in vitro and in vivo studies in oncology, particularly for investigating therapeutic strategies against MSI-high colorectal and gastric cancers.
Product Specifications
CAS Number
2869954-34-5
Product Name Alternative
WRN helicase, Werner syndrome RecQ helicase-IN-1, RNASynthesis, RNA Synthesis, DNA Synthesis, DNASynthesis, HRO-761
Field of Research
Cell Biology, Molecular Biology
Purity
98.24% (May vary between batches)
Solubility
DMSO:99.7 mg/mL (142.01 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (4.7 mM)
Smiles
C (C (NC1=C (Cl) C=C (C (F) (F) F) C=C1) =O) N2C=3N (C (=O) C (=C2CC) N4CCN (C (=O) C=5C (O) =C (C) N=CN5) CC4) N=C (N3) C=6CCOCC6
Molecular Formula
C31H31ClF3N9O5
Molecular Weight
702.08
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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