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P2X7 receptor antagonist-3

P2X7 receptor antagonist-3 is a highly potent and selective small molecule inhibitor of the P2X7 receptor, with IC50 values of 4.2 nM (human) and 6.8 nM (rat) . It is a valuable research tool for studying P2X7-mediated signaling in neuroinflammation, pain, and immune responses in both cellular and animal models.

Product Specifications

CAS Number

1627900-92-8

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Smiles

C (=O) (N1CC2=C (N (N=N2) C=3N=CC=CN3) CC1) C4=C (Cl) C (C (F) (F) F) =CC=C4

Molecular Formula

C17H12ClF3N6O

Molecular Weight

408.77

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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