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BRM/BRG1 ATP Inhibitor-3

BRM/BRG1 ATP Inhibitor-3 is a potent, dual-targeting small molecule that inhibits the BRM and BRG1 ATPases of the BAF complex with IC50 values of 10.4 nM and 19.3 nM, respectively. It is a valuable chemical probe for studying chromatin remodeling in cancer research and other BAF-related diseases, with utility in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

2368901-31-7

Field of Research

Epigenetics & Chromatin, Neuroscience; Epigenetics & Chromatin; Pharmacology & Drug Discovery

Smiles

N (C ([C@@H] (NC (=O) C1=CC=C (N) C=C1) CCSC) =O) C2=NC (C3=CC (=CC=C3) C=4C=CN=CC4) =CS2

Molecular Formula

C26H25N5O2S2

Molecular Weight

503.64

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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