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LC kinetic stabilizer-1

LC kinetic stabilizer-1 is a potent and selective small molecule that kinetically stabilizes amyloidogenic immunoglobulin light chain (LC) dimers. It demonstrates EC50 values of 140 nM for WIL-FL and 74.1 nM for the WIL-FLT46L/F49Y variant. This compound is a valuable research tool for investigating light chain amyloidosis (AL) in biochemical and cellular assays.

Product Specifications

CAS Number

2495750-19-9

Smiles

CC=1C=2C (=CC (N (CC) CC) =CC2) OC (=O) C1CCNC (NCC3=CC (=CC=C3) C4=CN=CN4) =O

Molecular Formula

C27H31N5O3

Molecular Weight

473.57

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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