KRAS G12D inhibitor 16
KRAS G12D Inhibitor 16 is a highly potent small molecule targeting the KRAS G12D mutation, with IC50 values of 0.7 nM and 0.35 μM for the mutant and wild-type proteins, respectively. It is a valuable research tool for studying KRAS-driven cancers such as pancreatic, colorectal, and non-small cell lung carcinomas in both in vitro and in vivo models.
Product Specifications
CAS Number
2648221-12-7
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
C (C1 (COC2=NC (=C3C (=N2) CN (CC3) C=4C5=C (C=C (O) C4) C=CC=C5I) N6CC7NC (C6) CC7) CC1) N8CCOCC8
Molecular Formula
C32H39IN6O3
Molecular Weight
682.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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