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Crozbaciclib fumarate

Crozbaciclib fumarate is a potent and selective small molecule inhibitor of CDK4 and CDK6, exhibiting half-maximal inhibitory concentrations (IC50) of 3 nM and 1 nM, respectively. It is utilized in cancer research to study cell cycle progression and has demonstrated antitumor activity in both cellular assays and in vivo models.

Product Specifications

CAS Number

2567494-39-5

Field of Research

Cell Biology

Smiles

C (=C/C (O) =O) \C (O) =O.CC=1C2 (C=3C (N1) =C (F) C=C (C3) C4=NC (NC5=CC=C (C=N5) C6CCN (C) CC6) =NC=C4F) CCCC2

Molecular Formula

C32H34F2N6O4

Molecular Weight

604.65

Storage Conditions

-20°C

Notes

For research use only.

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