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Theliatinib tartrate

Theliatinib tartrate is a potent, orally active, and highly selective ATP-competitive EGFR inhibitor, with a K_i of 0.05 nM. It shows strong activity against EGFR T790M/L858R mutants and >50-fold selectivity over other kinases, making it a valuable tool for in vitro and in vivo cancer research targeting EGFR-driven pathways.

Product Specifications

CAS Number

2413487-72-4

Field of Research

Cardiovascular Research, Signal Transduction

Smiles

[C@@H] ([C@H] (C (O) =O) O) (C (O) =O) O.N (C=1C2=C (C=C (OC) C (NC (=O) N3C[C@]4 ([C@@] (C3) (CCN4C) [H]) [H]) =C2) N=CN1) C5=CC (C#C) =CC=C5

Molecular Formula

C29H32N6O8

Molecular Weight

592.6

Storage Conditions

-20°C

Notes

For research use only.

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