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SARS-CoV-2 Mpro-IN-4

SARS-CoV-2 Mpro-IN-4 is a dual-target inhibitor of the viral Main Protease (Mpro, IC50=900 nM) and host Cathepsin L (CatL, IC50=60 nM) . It potently inhibits viral replication in cellular assays (IC50=8.2 nM in hACE2-A549 cells), making it a valuable chemical probe for studying coronavirus entry and replication mechanisms in vitro.

Product Specifications

Field of Research

Infectious Disease & Virology

Smiles

CCOC (=O) /C=C/[C@H] (C[C@@H]1CCNC1=O) NC (=O) [C@H] (CC2=CC=CC=C2) NC (=O) [C@@H] (CC3=CC=CC=C3) NC

Molecular Formula

C30H38N4O5

Molecular Weight

534.65

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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