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SARS-CoV-2 Mpro-IN-5

SARS-CoV-2 Mpro-IN-5 is a dual-target antiviral agent, inhibiting the viral Main Protease (Mpro; IC50=1800 nM) and host Cathepsin L (CatL; IC50=145 nM) . It effectively blocks viral replication in cellular models like hACE2-A549 cells (IC50=14.7 nM), making it a valuable chemical probe for studying coronavirus entry and replication mechanisms in vitro.

Product Specifications

Field of Research

Infectious Disease & Virology

Smiles

CCOC (=O) /C=C/[C@H] (C[C@@H]1CCNC1=O) NC (=O) [C@H] (CC2=CC=CC=C2) NC (=O) [C@@H] (CC3=CC=C (C=C3) F) NC (=O) OC (C) (C) C

Molecular Formula

C34H43FN4O7

Molecular Weight

638.73

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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