SARS-CoV-2 Mpro-IN-5
SARS-CoV-2 Mpro-IN-5 is a dual-target antiviral agent, inhibiting the viral Main Protease (Mpro; IC50=1800 nM) and host Cathepsin L (CatL; IC50=145 nM) . It effectively blocks viral replication in cellular models like hACE2-A549 cells (IC50=14.7 nM), making it a valuable chemical probe for studying coronavirus entry and replication mechanisms in vitro.
Product Specifications
Field of Research
Infectious Disease & Virology
Smiles
CCOC (=O) /C=C/[C@H] (C[C@@H]1CCNC1=O) NC (=O) [C@H] (CC2=CC=CC=C2) NC (=O) [C@@H] (CC3=CC=C (C=C3) F) NC (=O) OC (C) (C) C
Molecular Formula
C34H43FN4O7
Molecular Weight
638.73
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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