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SARS-CoV-2 Mpro-IN-6

SARS-CoV-2 Mpro-IN-6 is a potent, irreversible, and selective covalent inhibitor of the SARS-CoV-2 main protease (Mpro), with an IC50 of 0.18 μM. It shows no activity against key human proteases like cathepsins B, F, K, L, or caspase-3, making it a valuable tool compound for antiviral mechanism studies and inhibitor development in both biochemical and cellular assays.

Product Specifications

CAS Number

2768834-48-4

Field of Research

Infectious Disease & Virology

Smiles

C (NCC1=CC=CS1) (=O) [C@H]2N (CCN (C (CCl) =O) C2) C3=CC (Cl) =C (Cl) C=C3

Molecular Formula

C18H18Cl3N3O2S

Molecular Weight

446.78

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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