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NOD1/2 antagonist-1

This dual NOD1/NOD2 antagonist exhibits IC50 values of 1.13 μM and 0.77 μM, respectively, with a half-life of 67.6 minutes. It is a valuable research tool for studying innate immune signaling and has been shown in research to enhance the antitumor effects of chemotherapeutics like paclitaxel in experimental models.

Product Specifications

CAS Number

2704623-69-6

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology, Signal Transduction

Purity

99.69% (May vary between batches)

Solubility

DMSO:25 mg/mL (37.71 mM) ; H2O:< 1 mg/mL (insoluble)

Smiles

O=C (NCCCOC1=CC=C (C=C1) C (F) (F) F) C2=CC=3N=CN (C (=O) C3C=C2C=4C=CC=C (Cl) C4) CC (=O) N5CCCC (F) (F) C5

Molecular Formula

C32H28ClF5N4O4

Molecular Weight

663.03

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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