NOD1/2 antagonist-1
This dual NOD1/NOD2 antagonist exhibits IC50 values of 1.13 μM and 0.77 μM, respectively, with a half-life of 67.6 minutes. It is a valuable research tool for studying innate immune signaling and has been shown in research to enhance the antitumor effects of chemotherapeutics like paclitaxel in experimental models.
Product Specifications
CAS Number
2704623-69-6
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology, Signal Transduction
Purity
99.69% (May vary between batches)
Solubility
DMSO:25 mg/mL (37.71 mM) ; H2O:< 1 mg/mL (insoluble)
Smiles
O=C (NCCCOC1=CC=C (C=C1) C (F) (F) F) C2=CC=3N=CN (C (=O) C3C=C2C=4C=CC=C (Cl) C4) CC (=O) N5CCCC (F) (F) C5
Molecular Formula
C32H28ClF5N4O4
Molecular Weight
663.03
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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