SIRT6 activator 12q
12q is a potent, selective, and orally active SIRT6 activator with an IC50 of 0.58 μM, showing >300-fold selectivity over other sirtuins. It exhibits anticancer properties in vitro by inhibiting proliferation and migration, inducing apoptosis, and causing G2/M cell cycle arrest, supporting research in oncology and aging.
Product Specifications
CAS Number
2601734-99-8
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Purity
98.53% (May vary between batches)
Smiles
O=C (NC (C=1C=CC=CC1) C=2C=CC=CC2) C3=CC (=NC=4C=CC=CC43) C=5OC=6C=CC=CC6C5
Molecular Formula
C31H22N2O2
Molecular Weight
454.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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