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SIRT6 activator 12q

12q is a potent, selective, and orally active SIRT6 activator with an IC50 of 0.58 μM, showing >300-fold selectivity over other sirtuins. It exhibits anticancer properties in vitro by inhibiting proliferation and migration, inducing apoptosis, and causing G2/M cell cycle arrest, supporting research in oncology and aging.

Product Specifications

CAS Number

2601734-99-8

Field of Research

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Purity

98.53% (May vary between batches)

Smiles

O=C (NC (C=1C=CC=CC1) C=2C=CC=CC2) C3=CC (=NC=4C=CC=CC43) C=5OC=6C=CC=CC6C5

Molecular Formula

C31H22N2O2

Molecular Weight

454.52

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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