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Aurora Kinases-IN-3

Aurora Kinases-IN-3 is an orally bioavailable inhibitor of Aurora B kinase (AURKB) . Its primary mechanism involves disrupting the mitotic localization of AURKB rather than directly blocking its kinase activity toward histone H3. This compound is a valuable research tool for studying mitotic progression and has demonstrated utility in both cellular and in vivo models of cancer research.

Product Specifications

CAS Number

2840558-83-8

Field of Research

Cell Biology, Epigenetics & Chromatin

Smiles

O (C1=C (C=CC=N1) C=2C=C (OC) N=CC2) C3=CC (C (NC) =O) =CC (OC (F) (F) F) =C3

Molecular Formula

C20H16F3N3O4

Molecular Weight

419.35

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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