Aurora Kinases-IN-3
Aurora Kinases-IN-3 is an orally bioavailable inhibitor of Aurora B kinase (AURKB) . Its primary mechanism involves disrupting the mitotic localization of AURKB rather than directly blocking its kinase activity toward histone H3. This compound is a valuable research tool for studying mitotic progression and has demonstrated utility in both cellular and in vivo models of cancer research.
Product Specifications
CAS Number
2840558-83-8
Field of Research
Cell Biology, Epigenetics & Chromatin
Smiles
O (C1=C (C=CC=N1) C=2C=C (OC) N=CC2) C3=CC (C (NC) =O) =CC (OC (F) (F) F) =C3
Molecular Formula
C20H16F3N3O4
Molecular Weight
419.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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