GPR84 antagonist 2
GPR84 Antagonist 2 is a potent, selective, and orally active small molecule antagonist of GPR84 (IC50 = 8.95 nM) . It effectively inhibits calcium mobilization and chemotaxis in neutrophils and macrophages, making it a valuable research tool for investigating inflammatory conditions such as ulcerative colitis in both cellular and animal models.
Product Specifications
CAS Number
2244269-74-5
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
O=P (OC1=CC2=C (SC3=C1C=CC=C3) C=CC=C2Cl) (OC4=CC5=C (SC6=C4C=CC=C6) C=CC=C5Cl) [O-].[Na+]
Molecular Formula
C28H16Cl2NaO4PS2
Molecular Weight
605.42
Storage Conditions
-20°C
Notes
For research use only.
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