Antitumor agent-81
Antitumor agent-81 is a small molecule agonist that enhances the P62-RNF168 interaction, thereby inhibiting RNF168-mediated H2A ubiquitination and homologous recombination DNA repair. It demonstrates potent, dose-dependent suppression of tumor growth in mouse xenograft models, making it a valuable research tool for studying DNA damage response and cancer therapeutics.
Product Specifications
CAS Number
2765180-17-2
Field of Research
Cell Biology, Protein Biochemistry
Smiles
O (C) C=1C=C (N2C=C (N=N2) C3=CC4=C (C=C3) N=C (N) N=C4N) C=C (OC) C1OC
Molecular Formula
C19H19N7O3
Molecular Weight
393.4
Storage Conditions
-20°C
Notes
For research use only.
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