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Lapatinib tosylate

Lapatinib ditosylate is an orally bioavailable, dual tyrosine kinase inhibitor targeting EGFR and ErbB-2 (HER2) with IC50 values of 10.2 nM and 9.8 nM, respectively. It is widely used in vitro and in vivo for cancer research, particularly in studies of breast cancer and other HER2/EGFR-driven malignancies.

Product Specifications

CAS Number

1187538-35-7

Field of Research

Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Smiles

O=S (=O) (O) C1=CC=C (C=C1) C.O=S (=O) (C) CCNCC=1OC (=CC1) C=2C=CC3=NC=NC (NC4=CC=C (OCC=5C=CC=C (F) C5) C (Cl) =C4) =C3C2

Molecular Formula

C36H34ClFN4O7S2

Molecular Weight

753.26

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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