AT1R antagonist 1
AT1R Antagonist 1 (compound 10) is a potent and selective angiotensin II type 1 receptor (AT1R) ligand with a binding affinity (Ki) of 8.5 nM. This small molecule inhibitor is a valuable pharmacological tool for investigating the renin-angiotensin system in cardiovascular and renal research, applicable in both in vitro binding assays and in vivo functional studies.
Product Specifications
CAS Number
2848719-80-0
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
CCCC1=NC (=C (S1) S (=O) (=O) NC (=O) OCCCC (F) (F) F) C2=CC=C (C=C2) CN3C (=NC4=C3N=C (C=C4C) C) CC
Molecular Formula
C28H32F3N5O4S2
Molecular Weight
623.71
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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