VEGFR-2/BRAF-IN-1
VEGFR-2/BRAF-IN-1 is a potent dual kinase inhibitor targeting VEGFR-2 and both wild-type and V600E mutant BRAF, with IC50 values in the nanomolar range. It induces apoptosis and G1/S phase cell cycle arrest, supporting its use in cancer research for in vitro mechanistic studies and in vivo models of angiogenesis and tumor growth.
Product Specifications
Field of Research
Cardiovascular Research, Cardiovascular Research; Cell Biology, Cell Biology, Signal Transduction
Smiles
C1CCC2=C (C1) C3=C (S2) N=C (N (C3=O) C4=CC=C (C=C4) Cl) SCC (=O) NNC (=O) NC5=CC (=C (C=C5) Cl) C (F) (F) F
Molecular Formula
C26H20Cl2F3N5O3S2
Molecular Weight
642.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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