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VEGFR-2/BRAF-IN-2

VEGFR-2/BRAF-IN-2 is a dual kinase inhibitor with potent activity against VEGFR-2, BRAF V600E, and BRAF WT (IC50 values: 0.111 μM, 0.089 μM, and 0.071 μM, respectively) . It induces apoptosis and G1 phase cell cycle arrest, making it a useful research tool for studying angiogenesis and oncogenic signaling in cancer models.

Product Specifications

Field of Research

Cardiovascular Research, Cardiovascular Research; Cell Biology, Cell Biology, Signal Transduction

Smiles

C1CCC2=C (C1) C3=C (S2) N=C (N (C3=O) C4=CC=C (C=C4) Cl) SCC (=O) NNC (=O) NC5=CC=CC (=C5) C (F) (F) F

Molecular Formula

C26H21ClF3N5O3S2

Molecular Weight

608.05

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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