STING modulator-3
STING modulator-3 is a potent small molecule inhibitor of the R232 STING variant with a Ki of 43.1 nM. It selectively blocks this STING isoform without affecting IRF-3 activation or TNF-β production in THP-1 cells. This compound is a valuable tool for dissecting STING-dependent signaling in immunological and inflammatory research, both in vitro and in vivo.
Product Specifications
CAS Number
2839639-94-8
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
CN1C (C2=C3C (=CC (C (N) =O) =N2) N (C) N=C3) =NC (=C1) C=4N (CC#N) N=C (C) C4
Molecular Formula
C18H17N9O
Molecular Weight
375.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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