STING modulator-4
STING Modulator-4 is a competitive inhibitor of the R232H STING variant with a K_i of 0.0933 μM, though it shows weak activity (EC_50 >10 μM) for p-IRF3 activation in THP-1 cells. This small molecule is a useful research tool for investigating STING signaling and its variants in biochemical and cellular assays.
Product Specifications
CAS Number
2839639-72-2
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
CN1C (C2=C3C (=CC (C (N) =O) =N2) N (C) N=C3) =NC (=C1) C=4N (CC) N=CC4
Molecular Formula
C17H18N8O
Molecular Weight
350.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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