CRIPGBM chloride
CRIPGBM chloride is a small molecule that promotes apoptosis in glioblastoma stem cells by targeting RIPK2. It functions as a molecular switch, shifting RIPK2 binding from pro-survival TAK1 complexes to pro-apoptotic caspase-1 complexes. This compound is a useful research tool for studying cell death mechanisms in brain tumor models, both in vitro and in vivo.
Product Specifications
CAS Number
2361988-77-2
Field of Research
Cell Biology, Protein Biochemistry, Signal Transduction
Purity
99.75% (May vary between batches)
Solubility
DMSO:16 mg/mL (35.8 mM)
Smiles
[Cl-].O=C1C=2C=CC=CC2C (=O) C3=C1N (C (=[N+]3CC4=CC=C (F) C=C4) C) CC=5C=CC=CC5
Molecular Formula
C26H20ClFN2O2
Molecular Weight
446.9
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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