PD-1/PD-L1-IN-23
PD-1/PD-L1-IN-23 is an orally bioavailable ester prodrug of the benzooxadiazole-based PD-1/PD-L1 inhibitor L7. It demonstrates potent in vitro binding inhibition and has shown significant antitumor efficacy in syngeneic mouse models and studies using PD-L1 humanized mice.
Product Specifications
CAS Number
2597056-04-5
Field of Research
Cancer Biology; Immunology & Inflammation, Cell Biology, Immunology & Inflammation
Smiles
O (CC1=CC=2C (C=C1) =NON2) C3=C (CN[C@@H] (C (OCC) =O) CO) C=C (Cl) C (OCC4=C (Br) C (=CC=C4) C5=CC=CC=C5) =C3.Cl
Molecular Formula
C32H30BrCl2N3O6
Molecular Weight
703.41
Storage Conditions
-20°C
Notes
For research use only.
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