Nrf2 activator-6
Nrf2 Activator-6 is a potent, small molecule Nrf2 inducer belonging to the tetrahydroisoquinoline class. It disrupts the Keap1-Nrf2 protein-protein interaction with an IC50 of 5 nM, promoting antioxidant gene expression. This compound is a valuable research tool for studying oxidative stress in models of neurodegenerative and inflammatory diseases.
Product Specifications
CAS Number
2728780-74-1
Field of Research
Immunology & Inflammation
Smiles
C ([C@@H]1C=2C (CCN1C (=O) [C@H]3[C@] (C (O) =O) (C) CCC3) =C (Cl) C=C (F) C2OCC4=C5N (N=N4) CCCC5) N6CC7 (CC6=O) CC7
Molecular Formula
C31H37ClFN5O5
Molecular Weight
614.11
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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