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(Rac) -Lonafarnib

Lonafarnib (Sch66336 racemate) is a potent, orally bioavailable farnesyltransferase inhibitor with low nM IC50 values against H-, K-, and N-ras isoforms. It is also active against hepatitis delta virus (HDV) and has been utilized in both in vitro and in vivo cancer and virology research models.

Product Specifications

CAS Number

193275-86-4

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Smiles

BrC1=C2C (C=3C (CCC2=CC (Cl) =C1) =CC (Br) =CN3) C4CCN (C (CC5CCN (C (N) =O) CC5) =O) CC4

Molecular Formula

C27H31Br2ClN4O2

Molecular Weight

638.82

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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