(Rac) -Lonafarnib
Lonafarnib (Sch66336 racemate) is a potent, orally bioavailable farnesyltransferase inhibitor with low nM IC50 values against H-, K-, and N-ras isoforms. It is also active against hepatitis delta virus (HDV) and has been utilized in both in vitro and in vivo cancer and virology research models.
Product Specifications
CAS Number
193275-86-4
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
BrC1=C2C (C=3C (CCC2=CC (Cl) =C1) =CC (Br) =CN3) C4CCN (C (CC5CCN (C (N) =O) CC5) =O) CC4
Molecular Formula
C27H31Br2ClN4O2
Molecular Weight
638.82
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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