3-epi-Vitamin D3
3-epi-Vitamin D3 (Epicholecalciferol) is a Vitamin D3 analog that acts as a Hedgehog signaling pathway inhibitor, demonstrating activity with an IC50 of 39.2 μM in U87MG glioblastoma cells. This small molecule is used in research to study Hedgehog pathway-driven cancers, such as medulloblastoma and basal cell carcinoma, in both cellular and animal models.
Product Specifications
CAS Number
57651-82-8
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Smiles
C[C@@]12[C@] (/C (=C/C=C/3\C (=C) CC[C@@H] (O) C3) /CCC1) (CC[C@@]2 ([C@@H] (CCCC (C) C) C) [H]) [H]
Molecular Formula
C27H44O
Molecular Weight
384.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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