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P-gp inhibitor 2

P-gp Inhibitor 2 is a potent small molecule antagonist of P-glycoprotein, demonstrating efficacy in reversing multidrug resistance. It shows an IC50 of 0.22 μM against doxorubicin-resistant SW620 Ad300 cells and is a valuable research tool for studying chemoresistance in oncology, applicable in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

2408406-89-1

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Smiles

O=C1N2[C@@] ([C@H] (C=3C1=CC=CC3) C=4C=C5C (=C (OC) C4) OCO5) (CN (C (C) =O) [C@@H] (C (=O) C6=CC=CC=C6) C2) [H]

Molecular Formula

C29H26N2O6

Molecular Weight

498.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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