P-gp inhibitor 2
P-gp Inhibitor 2 is a potent small molecule antagonist of P-glycoprotein, demonstrating efficacy in reversing multidrug resistance. It shows an IC50 of 0.22 μM against doxorubicin-resistant SW620 Ad300 cells and is a valuable research tool for studying chemoresistance in oncology, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2408406-89-1
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
O=C1N2[C@@] ([C@H] (C=3C1=CC=CC3) C=4C=C5C (=C (OC) C4) OCO5) (CN (C (C) =O) [C@@H] (C (=O) C6=CC=CC=C6) C2) [H]
Molecular Formula
C29H26N2O6
Molecular Weight
498.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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