(R) -eIF4A3-IN-2
(R) -eIF4A3-IN-2 is the less active enantiomer of the selective, noncompetitive eIF4A3 inhibitor eIF4A3-IN-2, exhibiting an IC50 of 110 nM. This compound serves as a critical tool for studying exon junction complex (EJC) function and nonsense-mediated mRNA decay (NMD) in both cellular and biochemical assays.
Product Specifications
CAS Number
2095484-82-3
Field of Research
Cell Biology
Smiles
C (=O) (N1[C@@H] (CN (C (=O) C2=C3N (N=C2) C=C (Br) C=C3) CC1) C4=CC=C (Cl) C=C4) C5=CC=C (Br) C=C5
Molecular Formula
C25H19Br2ClN4O2
Molecular Weight
602.71
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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