E7090 succinate
E7090 succinate is a potent and orally bioavailable small molecule inhibitor selectively targeting FGFR1-3 tyrosine kinases with sub-nanomolar IC50 values, while showing much lower activity against FGFR4. It is a valuable research tool for investigating FGFR-driven pathologies, including certain cancers, in both cellular and animal models.
Product Specifications
CAS Number
1879965-80-6
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
O=C (CCC (O) =O) O.O=C (C1=CC=C (C2CCN (CC2) CCO) C=C1) NC3=NC=CC (OC4=CC5=C (C=C4OCCOC) N (C (NC) =O) C=C5) =C3.O=C (CCC (O) =O) O.O=C (C6=CC=C (C7CCN (CC7) CCO) C=C6) NC8=NC=CC (OC9=CC%10=C (C=C9OCCOC) N (C (NC) =O) C=C%10) =C8.O=C (CCC (O) =O) O
Molecular Formula
C76H92N10O24
Molecular Weight
1529.60
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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