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TTK inhibitor 3

TTK inhibitor 3 is a highly potent and selective small molecule targeting the spindle assembly checkpoint kinase TTK, with an IC50 of 3.0 nM. It serves as a valuable chemical probe for studying mitosis and has demonstrated utility in both in vitro biochemical assays and in vivo cancer research models investigating aneuploidy and tumorigenesis.

Product Specifications

CAS Number

2820453-41-4

Field of Research

Neuroscience; Pharmacology & Drug Discovery, Signal Transduction

Purity

99.44% (May vary between batches)

Smiles

O=C1C2=CC (=CN2CCN1C=3C (=CC=CC3CC) CC) C=4N=C (N=C5NC=CC54) NC6=CC=C (C=C6OC) N7CCC (C (=O) N8CC9 (C8) CN (C) C9) CC7

Molecular Formula

C42H49N9O3

Molecular Weight

727.9

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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