C-Met/HDAC-IN-2

C-Met/HDAC-IN-2 is a dual-action small molecule with potent inhibitory activity against c-Met (IC50=5.40 nM) and HDAC1 (IC50=18.49 nM) . It demonstrates robust anti-proliferative effects in vitro, inducing cell cycle arrest and apoptosis in cancer cell lines like HCT-116, supporting its investigation for overcoming therapeutic resistance.