Keap1-Nrf2-IN-6
Keap1-Nrf2-IN-6 is a highly potent and selective small molecule inhibitor that disrupts the Keap1-Nrf2 protein-protein interaction, with an IC50 of 41 nM and a Kd of 68 nM. This inhibitor is a valuable chemical probe for investigating the Nrf2-mediated antioxidant response pathway in both cellular and animal models of oxidative stress and inflammation.
Product Specifications
Field of Research
Cancer Biology, Immunology & Inflammation
Smiles
CC (=O) N1CCC[C@H]1C (=O) N[C@@H]2COC (=O) C3=CC=CC (=C3CSC[C@@H] (NC2=O) C (=O) N (C) C) C4=CC=C (C=C4) C (=O) O
Molecular Formula
C30H34N4O8S
Molecular Weight
610.68
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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